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Directory: Division of General and Gastrointestinal Surgery and Division of Colorectal Surgery (below)

Mark W. Arnold, M.D.


Staff photo

410 W 10th Ave
Columbus, OH 43210

Phone: (614) 293-8133

Email: arnold.16@osu.edu

 

Current OSU Appointments

Professor-Clinical, Colon and Rectal Surgery

Physician, FGP-Colon and Rectal Surgery

 

Certifications

1981 - present Florida Medical License: Florida Medical Board
1983 - present Ohio Medical License: State Medical Board of Ohio
1989 - present Board Certified Surgeon: American Board of Surgery
1990 - present Board Certified Surgeon: American Board of Colorectal Surgery
1996 - present Re-certification Board Certified Surgeon: American Board of Colorectal Surgery
1997 - present Board Certified Surgeon: American Board of Surgery
2007 - present Re-certification Board Certified Surgeon: American Board of Colorectal Surgery
2007 - present Board Certified Surgeon: American Board of Surgery
 

Chapters in Books

Arnold MW. "Constipation and Incontinence: an update in diagnosis & treatment." In Inside Tract. -. Inside Tract, January 1989.

Arnold MW, Schneebaum S, Martin EW. "CEA second-look surgery." In Colorectal Cancer. H.J. Wanebo (Ed.) ed. Edited by H.J. Wanebo (Ed). 389-404. St. Louis: C.V. Mosby Inc., January 1993.

Schneebaum S, Arnold MW, Nag S, Mojzisik C, Martin EW Jr. "The utility of the RIGS system in recurrent colorectal cancer." In Radioimmunoguided Surgery (RIGS) in the Detection and Treatment of Colorectal Cancer.. Edited by Martin EW Jr. 135-146. Austin: R.G. Landes Company, January 1994.

Arnold MW, Petty L, Schneebaum S. "The utility of the RIGS system in primary colorectal cancer." In Radioimmunoguided Surgery (RIGS) in the Detection and Treatment of Colorectal Cancer. Edited by Martin EW Jr. (Ed). 125-134. Austin: R. G. Landes Company, January 1994.

Arnold MW, Schneebaum S, Martin EW Jr. "Second-look operations." In Cancer of the Colon, Rectum, and Anus. Edited by Cohen, Winawer, Friedman, Gunderson. 799-803. Columbus: McGraw-Hill, Inc, January 1994.

Schneebaum S, Arnold MW, Martin EW Jr. "The utility of radioimmunoguided surgery in colorectal cancer." In Surgery of the Colon, Rectum, and Anus. Edited by Mazier, Levien, Luehtenfeld, Senagore. 460-469. Austin: W.B. Saunders, January 1995.

Arnold MW, (guest editor). "Radioimmunoguided diagnosis in surgery for colorectal cancer." In Seminars in Colon & Rectal Surgery. Edited by Schoetz DJ Jr. 183-247. Austin: WB Saunders, January 1995.

Arnold MW, Schneebaum S, Staubus AE, Martin EW Jr. "Peritoneal carcinomatosis and radioimmunoguided surgery." In Peritoneal Carcinomatosis Diagnosis and Treatment. Edited by Sugarbaker PE. 193-209. Boston, MA: Kluwer Academic Publishers, January 1996.

Arnold MW, Schneebaum S, Martin EW Jr. "Radioimmunoguided surgery in the treatment and evaluation of rectal cancer patients." In Cancer Control. (3) 42-45. January 1996.

Arnold MW,. "Radiolabeled Antibodies: Current Uses in Immunoscintigraphy and Radioimmunoguided Surgery." In Perspectives in Colon and Rectal Surgery. 73-89. New York: Thieme Publishers, January 1999.

Arnold MW,. "Rising Serum Carcinoembryonic Antigen Levels: Imaging Techniques and Second-Look Surgery." In Surgery. Edited by Corson JD, Williamson RCN. 3-24. 27. New York: Harcourt Health Sciences, January 2001.

 

Degrees

1975 B.A., University of Virginia

 

Editorial Activities

1998 - 2007 Diseases of the Colon and Rectum
 

Honors

0 .
1989 Chief Resident in Surgery. Upjohn Achievement Award.
1991 Excellence in Teaching Award. The Ohio State University.
1999 Department of Surgery Teaching Award. The Ohio State University.
2001 The Leadership Council for Clinical Value Enhancement Award. The Leadership Council.
2002 Excellence in Teaching Award. The Ohio State University College of Medicine.
2002 Alpha Omega Alpha. Alpha Omega Alpha.
2005 America's Best Doctors. U.S. News & World Report.
2007 America's Best Doctors. U.S. News & World Report.
2008 Distinguished Educator Award. The Ohio State University Medical Center.
2010 Physicain of the Month Award. Tim Park, M.D. Phyiscian Director of Perioperative Services.
2010 American's Best Doctors. U.S. News & World Report.
2011 American's Best Doctors. U.S. News & World Report.
 

Journal Articles

Arnold, MW, Charney AN, Johnstone N. "Acute respiratory alkalosis and acidosis and rabbit intestinal on transport in vivo." Am J Physiol. Vol. 244, no. 1983. (January 1983.): 145-50.

Feldman GM, Arnold, MW, Charney AN. "On the mechanism of luminal CO2 generation during jejunal bicarbonate absorption." Am J Physio. Vol. 246, no. 9. (January 1984.): G687-694.

Buechter KJ, Arnold, MW, Steele B, Martin L, Byers P, Gomez G, Zeppa R, Augenstein J. "The use of serum amylase and lipase in evaluating and managing blunt abdominal trauma." The Am Surgeon. Vol. 56, no. 4. (January 1990.): 204-208.

Arnold, MW, Stewart WRC, Aguilar PS. "Rectocele repair. Four years experience." Dis Colon Rectum. Vol. 33, (January 1990.): 684-687.

Arnold, MW, Aguilar PS, Stewart WRC. "Vaginography:an easy and safe technique for diagnosis of colovaginal fistulas." Dis Colon Rectum. Vol. 33, no. 4. (January 1990.): 344-345.

Wise WE Jr, Padmanabhan A, Meesig DM, Arnold, MW, Aguilar PS, Stewart WRC. "Abdominal colon and rectal operations in the elderly." Dis Colon Rectum. Vol. 34, (January 1991.): 959-963.

Wise WE Jr, Aguilar PS, Padmanabhan A, Meesig DM, Arnold, MW, Stewart WRC. "Surgical treatment of low rectovaginal fistulas." Dis Colon Rectum. Vol. 34, (January 1991.): 271-274.

Cho CC, Taylor CW III, Padmanabhan A, Arnold, MW, Aguilar PS, Meesig DM, Hartmann RS, Khanduja KS, Rahman SM, Stewart WRC. "Squamous-cell carcinoma of the anal canal: management with combined chemo-radiation therapy." Dis Colon Rectum. Vol. 34, (January 1991.): 675-678.

Arnold, MW, Schneebaum S, Berens A, Mojzisik C, Hinkle G, Martin EW Jr.. "Radioimmunoguided surgery challenges traditional decision making in patients with primary colorectal cancer." Surgery. Vol. 4, no. 112. (October 1992.): 624-9; discusssion 629.

Townsend MC, Flancbaum LJ, Cloutier CT, Arnold, MW. "Early postlaparotomy percutaneous endoscopic gastrostomy." Surg Gynecol Obstet. Vol. 174, (January 1992.): 46-48.

Schneebaum S, Lange MK, Arnold, MW, Ralston J, Dumond DA, Martin EW Jr.. "Intraperitoneal hyperthermic perfusion for recurrent colorectal cancer - feasibility study." Regional Cancer Treatment. Vol. 4, (January 1992.): 277-281.

Arnold, MW, Schneebaum S, Berens A, Petty L, Mojzisik C, Hinkle G, Martin EW Jr.. "Intraoperative detection of colorectal cancer with radioimmunoguided surgery (RIGS) and CC49: a second generation monoclonal antibody (MAb).." Ann Surg. Vol. 216, (January 1992.): 627-632.

Schneebaum S, Arnold, MW, Young D, LaValle GJ, Petty L, Berens A, Mojzisik C, Martin EW Jr.. "The role of carcinoembryonic antigen in predicting resectability of recurrent colorectal cancer." Dis Colon Rectum. Vol. 36, (January 1993.): 810-815.

Schneebaum S, Arnold, MW, Martin EW Jr. "Adjuvant treatment for rectal cancer: current status.." Oncology. Vol. 7, (January 1993.): 83-101.

Mutabagani KH, Townsend MC, Arnold, MW. "PEG ileus a preventable complication." Sugical Endoscopy. Vol. 8, (January 1994.): 694-697.

Bertsch DJ, Burak WE Jr, Young DC, Arnold, MW, Martin EW Jr. "Radioimmunoguided surgery system improves survival for patients with recurrent colorectal cancer." Surgery. Vol. 118, (January 1995.): 634-639.

Arnold, MW, Young DC, Hitchcock CL, Schneebaum S, Martin EW Jr. "Radioimmunoguided surgery in primary colorectal carcinoma: an intraoperative prognostic tool and adjuvant to traditional staging." Am J Surg. Vol. 170, (January 1995.): 315-318.

Schneebaum S, Arnold, MW, Houchens DP, Greenson JK, Cote RJ, Hitchcock CL, Young DC, Mojzisik CM, Martin EW Jr. "The significance of intraoperative periportal lymph node metastasis identification in patients with colorectal carcinoma." Cancer. Vol. 75, (January 1995.): 2809-2817.

Burak WE, Schneebaum S, Kim JA, Arnold, MW, Hinkle G, Berens A, Mojzisik C, Martin EW Jr. "A pilot study evaluating the intraoperative localization of radiolabeled monoclonal antibody (MAb) CC83 in patients with metastatic colorectal carcinoma." Surgery. Vol. 118, (January 1995.): 103-108.

Hitchcock CL, Arnold, MW, Young DC, Schneebaum S, Martin EW Jr. "Tag-72 expression in lymph nodes and RIGS (Letter to the Editor with Author’s Reply).." Disease of Colon and Rectum. Vol. 4, no. 3. (January 1996.): 473-475.

Schneebaum S, Arnold, MW, Staubus AE, Martin EW Jr. "Peritoneal carcinomatosis and radioimmunoguided surgery." Cancer Treat Res. Vol. 82, (January 1996.): 193-209.

Schneebaum S, Arnold MW, Staubus A, Young DC, Dumond D, Martin EW Jr.. "Intraperitoneal hyperthermic perfusion with Mitomycin C for colorectal cancer with peritoneal metastases." Annals of Surgical Oncology. Vol. 3, (January 1996.): 44-50.

Arnold, MW, Schneebaum S, Martin EW Jr. "Radioimmunoguided Surgery in the Treatment and Evaluation of Rectal Cancer Patients." Cancer Control. Vol. 1, no. 3. (January 1996.): 42-45.

Arnold, MW, Hitchcock CL, Young DC, Burak WE, Bertsch DJ, Martin EW Jr. "Intraabdominal patterns of disease dissemination in colorectal cancer identified using radioimmunoguided surgery (RIGS." Col Rectum. Vol. 39, (January 1996.): 509-513.

Arnold, MW, Bertsch DJ, Burak WE, Young DC, Martin EW Jr. "Radioimmunoguided surgery (RIGS) for colorectal cancer Radioimmunoguided surgery (RIGS) fo rcolorectal cancer." Ann Surg Onc. Vol. 3(3), (January 1996.): 310-316.

Cote RJ, Houchens DP, Hitchcock CL, Saad AD, Nines RG, gREENSON jk, Schneebaum S, Arnold, MW, Martin EW Jr.. "Intraoperative detection of occult colon cancer micrometastases using 125I-radiolabled monoclonal antibody CC49." Cancer. Vol. 3, (January 1996.): 613-620.

Bertsch DJ, Burak WE, Young DC, Arnold MW, Martin EW Jr.. "Radioimmunoguided surgery (RIGS) for colorectal cancer." Ann Surg Onc. Vol. 3, no. 3. (January 1996.): 310-316.

Barbera-Guillem E, Arnold, MW, Nelson MB, Martin EW Jr. "First results for resetting the antitumor immune response by immune corrective surgery in colon cancer." Am J Surg. Vol. 176, (January 1998.): 339-343.

Nieroda CA, Arnold, MW Barbera-Guillem E, Martin EW Jr. "Lymphadenectomy in colorectal carcinoma." Chirurg. Vol. 69, (January 1998.): 717-724.

Arnold MW, Young DC, Hitchcock CL, Barbera-Guillem E, Nieroda C, Martin EW Jr. "Staging of colorectal cancer: biology versus morphology." Dis Colon Rectum. Vol. 41, (January 1998.): 1482-1487.

Hitchcock CL, Sampsel J, Young DC, Martin EW Jr, Arnold MW. "Limitations with light microscopy in the detection of colorectal cancer cells." Dis Colon Rectum. Vol. 42, (January 1999.): 1046-1052.

Dasai DC, Arnold MW, Saha S, Hinkle G, Sobel D, Fry J, DePalatis LR, Mantil J, Satter M, Martin EW Jr. "Correlative whole-body FDG-PET and intraoperative gamma detection of FDG distribution in colorectal cancer." Clin Pos Imag. Vol. 3, (January 2000.): 189-196.

Zervos EE, Badgwell BD, Burak WE Jr, Arnold MW, Martin EW Jr.. "Fluorodeoxyglucose positron emission tomography as an adjunct to carcinoembryonic antigen in the management of patients with presumed recurrent colorectal cancer and nondiagnostic radiologic workup." Surgery. Vol. 130, (January 2001.): 636-644.

Johnson K, Bakhsh A, Young D, Martin E Jr, Arnold MW. "Correlating computed tomography and positron emission tomography scan with operative findings in metastatic colorectal cancer." Dis Colon Rectum. Vol. 44, (January 2001.): 354-.

Desai DC; Zervos EE; Arnold MW; Burak WE Jr; Mantil J; Martin EW Jr. "Positron emission tomography affects surgical management in recurrent colorectal cancer patients.." Annals Of Surgical Oncology. Vol. 10, no. 1. (January 2003.): 59-.

Desai D, Zervos E, Arnold MW, Burak W, Mantil J , Martin E. "Positron Emission Tomography Affects Surgical Management In Recurrent Colorectal Cancer Patients." Annals of Surgical Oncology. Vol. 1, no. 10. (January 2003.): 59-64.

Agnese DM, Abdessalam SF, Burak WE Jr, Arnold MW, Soble D, Hinkle GH, Young D; Khazaeli MB, Martin EW Jr. "Pilot study using a humanized CC49 monoclonal antibody (HuCC49DeltaCH2) to localize recurrent colorectal carcinoma.." Annals Of Surgical Oncology. Vol. 11, no. 2. (February 2004.): -.

Bloomston M; Kaufman H; Winston J; Arnold MW; Martin E. "Surgical management of colorectal cancer in the laparoscopic era: a review of prospective randomized trials.." Journal Of The National Comprehensive Cancer Network: JNCCN. Vol. 3, no. 4. (July 2005.): 517-524.

Arnold MW, Patterson AF, Tang L.. "Has implementation of the 80-hour work week made a career in surgery more appealing to medical students?." Am J Surg. Vol. 189, (January 2005.): 129-133.

Hampel H, Frankel WL, Martin E, Arnold MW, Khanduja K, Kuebler P, Nakagawa H, Sotamaa K, Prior TW, Westman J, Panescu J, Fix D, Lockman J, Comeras I, de la Chapelle A. "Screeing for the Lynch syndrome (hereditary nonpolyposis colorectal cancer)." N Engl J Med. Vol. 18, no. 352. (May 2005.): 1851-1860.

Sun D, Bloomston M, Hinkle G, Al-Saif OH, Hall NC, Povoski SP, Arnold MW, Martin EW. "Radioimmunoguided Surgery (RIGS), PET/CT Image-guided surgery and fluorescence image-guided surgery: past, present and future." Journal of Surgical Oncology. Vol. 4, no. 96. (September 2007.): 297-308.

Hampel H, Frankel WL, Martin E, Arnold MW, Khanduja K, Kuebler P, Clendenning M, Sotamaa K, Prior T, Westman JA, Panescu J, Fix D, Lockman J, Lajeunesse J, Corneras I, de la Chapelle A. "Feasibility of Screening for Lynch Syndrome Among patients with Colorectal Cancer." Journal Clinical Oncology. (September 2008.): -.

Sandquist Mary K, Way David P, Patterson Anna F, Caniano Donna A, Arnold Mark W, Nwometh Benedict C.. "General Surgery Versus Specialty Rotations: A New Paradigm in Surgery Clerkships." Journal of Surgical Research. (May 2008.): -.

South Christopher D, Yearsley Martha, Martin Edward, Arnold, MW, Frankel Wendy, Hampel, Heather.. "Immunohistochemistry Staining for the Mismatch Repair Proteins in the Clinical Care of Colorectal Cancer Patients.." Genetics in Medicine. Vol. 11, no. 11. (November 2009.): 812-817.

Wang LS, Arnold, MW, Huang YW, Sardo C, Seguin C, Martin E, Huang TH, Riedl K, Schwartz S, Frankel W, Pearl D, Xu Y, Winston J 3rd, Yang GY, Stoner G.. "Modulation of Genetic and Epigenetic Biomarkers of Colorectal Cancer in Humans by Black Raspberries: A Phase I Pilot Study." Clin Cancer Res. Vol. 1, no. 17(3). (February 2011.): 598-610.

Povoski SP, Hatzaras IS, Mojzisik CM, Arnold, MW, Hinkle GH, Hitchcock CL, Young DC, Martin EW Jr.. "Antigen-Directed Cancer Surgery for Primary Colorectal Cancer: 15-year Survival Analysis.." Ann Surg Oncol. (July 2011.): -.

 

Inventions and Patents

Mark W. Arnold, Marlin O. Thurston. "Radiation-Based Laparoscopic Method for Determining Treatment Modality."

 

Presentations

"On the mechanism of jejunal bicarbonate absorption." Presented at American Gastroenterology Association, NY. (May 1981)

"Ektachern lipase levels in blunt abdominal trauma." Presented at American Association for Clinical Chemistry, New Orleans. (July 1988)

"Cancer risk and surveillance." Presented at Current Surgical and Medical Management of Ulcerative Colitis, Columbus, OH. (September 1989)

"Treatment of horseshoe fistulas by mucosal advancement flap." Presented at American Society of Colon and Rectal Surgeons- Podium Presentation, St. Louis, MI. (April 1990)

"Squamous cell carcinoma of the anal canal: management with combined chemo-radiation." Presented at American Society of Colon and Rectal Surgeons- Podium Presentation, St Louis, MI. (April 1990)

"Radioimmunoguided surgery primary colorectal cancer patients -- a prelimary report." Presented at European Conference of Clinical Oncology, Florence, IT|ITA. (October 1991)

"Vasoactive intestinal polypeptide (VIP) augments colonic C1-secretion evoked by distension-actived neural reflex pathways." Presented at American Gastroenterological Association, New Orleans, LA. (May 1991)

"Pre-phase 1 comparison of B72.3 (first generation MAb) to CC49 (second generation MAb) in colorectal patient using the RIGS system." Presented at Zollinger Surgical Society Meeting, Columbus, OH. (May 1991)

"Analysis of lymph nodes from patients injected with l-125 labeled monoclonal antibody CC49." Presented at American Association of Clinical Research, . (January 1992)

"Presence of occult tumor detected by injected 125 1-labeled monoclonal antibody CC49. Pro AACR 1992;33:A1893." Presented at American Association of Cancer Research, . (January 1992)

"Radioimmunoguided surgery challenges traditional decision making in primary colorectal cancer patients." Presented at Central Surgical Association Meeting, Madison, WI. (March 1992)

"Radioimmunoguided surgery in colorectal cancer: histologic and immunohistochemical analysis og lymph nodes from patients injected with 125l labeled monoclonal antibody CC49." Presented at Seventh International Conference on Monoclonal Antibody Immunoconjugatesfor Cancer, San Diego, CA. (March 1992)

"Radioimmunoguided surgery in colorectal cancer: histologic and immunohistochemical analysis of lympgh nodes from patients injected with 1251 labeled monoclonal CC49." Presented at 7th Annual International Conference on Monoclonal Antibody Immunoconjugates for Cancer, San Diego, CA. (March 1992)

"A second look approach to the primary colorectal cancer patient." Presented at Special International Columbus Meeting on Surgical Oncology, Genoa, IT|ITA. (December 1992)

"The importance of periportal lymph node metastasis identification for introperative decision making." Presented at The Society of Surgical Oncology Annual Meeting, New York, NY. (March 1992)

"A prephase 1 study of radiolabeled monoclonal antibody (MAb) CC83 in patient with metastatic colorectacl carcinoma undergoing radioimmunoguided surgery (RIGS)." Presented at American Society of Clinical Oncologists, . (January 1993)

"Treatment of local recurrences for colorectal carcinoma." Presented at Controversies and Problems in Gastrointestinal Surgery, New York, NY. (December 1993)

"Surgical radioimmunodetection of tumors in the world." Presented at Seminar of the Italian Association of Introperatory Radioimmunolocalization of Tumors (GISCRIS), Milano, IT|ITA. (December 1993)

"Minimal invasive surgery in cancer management: laparoscopic RIGS.." Presented at Minimal Invasive Surgery Symposium, 47th Annual Meeting, Houston, TX. (March 1994)

"Radioimmunoguided Surgery." Presented at General Surgery Grand Rounds, Edison, NJ. (November 1994)

"RIGS Bio-staging: introduction of a new staging system for colon and rectal cancer." Presented at Current Management of Rectal Cancer, International Symposium, fLORENCE, IT|ITA. (April 1994)

"RIGS and recurrent colorectal cancer." Presented at Current Management of Rectal Cancer, International Symposium, Florence, IT|ITA. (April 1994)

"Surgical radioimmunodetection of tumors in the world.." Presented at National Cancer Institute of Milano, Milan, IT|ITA. (December 1994)

"Radioimmunoguided surgery (RIGS) improves survival for recurrent colorectal cancer." Presented at Central Surgical Association, Cleveland, OH. (March 1995)

"Patterns of disease dissemination in colorectal cancer using radioimmunoguided surgery." Presented at American Society of Colorectal Surgeons, Montreal, Canada. (May 1995)

"The Cutting Edge, Surgical Advances in Cancer Treatment." Presented at Bellefonte Cancer Center, Ashland, KY. (April 1995)

"RIGS >95.." Presented at Grand Rounds, Columbus, OH. (September 1995)

"Radioimmunoguided Surgery (RIGS) in Colorectal Carcinoma." Presented at Rectal Cancer Surgical Management in the Light of Current Basic and Clinical Research International Symposium, Berlin, DE|DEU. (September 1995)

"Radioimmunoguided surgery (RIGS) challenges the traditions of rectal cancer staging." Presented at Rectal Cancer Surgical Management in the Light of Current Basic and Clinical Research, International Symposium, Berlin, DE|DEU. (September 1995)

"Radioimmunoguided Surgery (RIGS) in Colorectal Carcinoma." Presented at Ohio Chaper of American College of Surgeons, Cincinnati, OH. (May 1996)

"Overview of Purpose and Problem." Presented at Washington Symposium:New Techniques in Identification and Staging of Colorectal Cancer, Seattle, WA. (June 1996)

"Current Management in the Treatment of Recurrent Colorectal Cancer." Presented at Hoag Cancer Center Evening Symposium, Newport Beach, CA. (April 1997)

"Radioimmunoguided Surgery: An Update." Presented at American College of Surgerons 83rd Clinical Congress, Chicago, IL. (October 1997)

"Current Status of Radioimmunoguided Surgery." Presented at Surgery Grand Rounds, Seoul. (December 1997)

"Radioimmunoguided Surgery: An Update." Presented at 30th Annual Meeting of Korean Society of Coloproctology, Seoul. (December 1997)

"A Second Look at Second Look Surgery." Presented at 43rd Annual Meeting Ohio Chapter of American College of Surgeons, Columbus, OH. (May 1998)

"Colon Trauma: Alternatives to Primary Repair.." Presented at American College of Surgeons, Columbus, OH. (January 1999)

"CEA Testing and Nuclear Scintigraphy: Do They Help in Reoperation for Suspected Recurrence?." Presented at A Rational Approach to the Follow-up of the Colorectal Cancer Patient, Columbus, OH. (January 2000)

"FDG-PET as an adjunct to CEA in the management of patients with presumed Recurrent Colorectal Cancer and normal Radiologic work-up." Presented at Central Surgical Society, . (January 2001)

"Has implementation of the 80-hour work week made a career in surgery more appealing to medical student?." Presented at Association for Surgical Education, Houston, TX. (January 2004)

"Radioimmunoguided surgery (RIGS) in colorectal carcinoma." Presented at Ohio Chapter of American College of Surgeons, Cincinnati, OH. (November 2007)